New York, early 1960s. Against the backdrop of a vibrant music scene and tumultuous cultural upheaval, an enigmatic 19-year-old from Minnesota arrives in the West Village with his guitar and revolutionary talent, destined to change the course of American music.
Finding himself in a new era, and approaching retirement, Indy wrestles with fitting into a world that seems to have outgrown him. But as the tentacles of an all-too-familiar evil return in the form of an old rival, Indy must don his hat and pick up his whip once more to make sure an ancient and powerful artifact doesn't fall into the wrong hands.
When a kid accidentally triggers the universe's most lethal hunters' return to Earth, only a ragtag crew of ex-soldiers and a disgruntled female scientist can prevent the end of the human race.